It's not 42. It's the atonement of Christ.
There are a lot of problems out there, big and small. It's striking to me that, while the details vary, the answer to each is, ultimately, the perfect love of God, also known as the atonement of Jesus Christ. Done something you wish you hadn't that hurt someone? Christ's atonement can cleanse you and heal the person you harmed. Awful suffering that goes beyond anything that could possibly teach us patience or empathy? Christ's atonement will--somehow, in a way I can't explain--make it "OK" in the end. People judging other people unfairly? Let everyone involved apply the atonement in their lives and recognize themselves as imperfect but perfectible beings on their way to great glory.
I know: it sounds like a cop-out, like it's too good to be true. It sounds like a pie-in-the-sky opiate of the masses. But like any real love it should motivate us to do a lot, not to sit back. It is, really, the equivalent of what the Beatles said when they sang that "All you need is love" -- why do some liberals love that message but sometimes look down their noses at claims of a godly gift that is the ultimate form of love? I don't know.
But I know that God's love as manifested in Christ willingly dying for us despite his being sinless is probably a big part of the answer.
"In all these things we are more than conquerors through him who loved us. For I am convinced that neither death nor life, neither angels nor demons, neither the present nor the future, nor any powers, neither height nor depth, nor anything else in all creation, will be able to separate us from the love of God that is in Christ Jesus our Lord."